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Updated: Jul 4, 2025

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一项对增强格林类同类的亲和力,活性和稳定性的接合方法的调查

Juan J Esteban1, Julia R Mason1, Jakob Kaminski1

  • 1Department of Chemistry, University of Western Ontario 1151 Richmond Street London Ontario N6A 3K7 Canada lluyt@uwo.ca.

RSC medicinal chemistry
|January 29, 2024
PubMed
概括

用化学主质稳定格林 (生长激素分泌剂受体连接体) 提高了其结构和治疗应用的亲和力. Stapled 格林类似物显示出改善的蛋白解稳定性和受体结合.

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