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使用PTR-ToF-MS进行涂料喷涂和干燥期间的暴露评估

Srdjan Sabic¹, David Bell², Bojan Gasic³

¹Institute for Atmospheric and Climate Science, ETH Zurich, Zurich, Switzerland.

Frontiers in public health

|January 29, 2024

概括

在喷和干燥过程中,工人接触溶剂对健康构成风险. 时间分辨率测量显示,通风对溶剂度产生重大影响,突出了改善工作场所安全暴露模型的必要性.

科学领域:

职业卫生职业卫生职业卫生
环境化学环境化学
工业过程监控工业过程监控

背景情况:

喷职业产品会因为空气中的颗粒和气体而造成健康风险.
准确的暴露评估对于工人安全至关重要.
现有的风险模型可能无法完全捕捉现实世界的情况.

研究的目的:

调查工作场所在喷雾和干燥过程中使用时间分辨率测量对溶剂的暴露.
将实时曝光数据与已建立的曝光模型的预测进行比较.
识别当前模型的局限性,并提出改进建议.

主要方法:

使用1秒分辨率的飞行时间质谱 (PTR-ToF-MS) 进行质子转移反应.
监测特定溶剂 (乙,乙醇,乙乙烯,烯,1-甲基-2-乙烯) 的气相度.
在不同的通风条件下,在户外喷和室内干燥期间进行测量.

主要成果:

在喷过程中,挥发性溶剂 (乙,乙醇) 主要暴露,受风的影响.
干燥阶段的暴露依赖于通风;高通风导致了溶剂的快速衰变.
干燥过程中的低通风导致溶剂度达到峰值,有时超过喷雾暴露水平.
与模型相比:ECETOC TRA和Stoffenmanager都在范围内,但并不总是保守的.
在一个例子中,ART高估了挥发性溶剂暴露,并低估了1M2PA.
ECETOC TRA和ART缺乏干燥阶段预测;Stoffenmanager的干燥预测是有限的.

结论:

喷雾云动态和干燥过程中的溶剂蒸发都是关键的暴露因素.
目前的暴露模型在预测现实世界的溶剂度方面存在局限性,特别是在干燥过程中.
需要改进的模型和全面的数据集来准确地评估工作场所的暴露,并提高安全性.

关键词:

暴露模型中的暴露模型.质子转移反应飞行时间质谱学质谱学.喷雾应用喷雾应用挥发性有机化合物挥发性有机化合物工作场所的暴露在工作场所.

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