产科关节损伤中的亚裔-白人差异:系统性审查和元分析
Meejin Park1, Susitha Wanigaratne2, Rohan D'Souza3,4
1Faculty of Health Sciences, Department of Global Health, McMaster University, Hamilton, Ontario, Canada (Ms Park).
AJOG global reports
|January 29, 2024
概括
与高收入国家的白人相比,亚洲人患产科关节损伤的风险更高. 需要进一步的研究来了解这种差异的原因.
科学领域:
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 产妇关节损伤 (OASIS) 是一种严重的周围裂,约有4.4%的阴道分娩发生.
- 在高收入国家观察到OASIS发病率的种族和民族差异.
- 研究表明,与西方国家的白人相比,亚洲人的OASIS风险更高.
研究的目的:
- 系统地审查和对现有关于高收入非亚洲国家的种族/种族和OASIS关系的研究进行元分析.
- 量化亚裔与白人身份识别与OASIS风险之间的关联.
- 探索亚洲人群中潜在的亚组差异.
主要方法:
- 在主要的医疗数据库 (MEDLINE,Ovid,Embase,EmCare,Cochrane) 进行了全面的搜索.
- 包括使用相关关键词和受控词汇的观察性研究 (横截面,病例控制,队列).
- 使用RevMan进行了元分析,并进行了子组分析和元回归来评估异质性.
主要成果:
- 分析包括27项研究,涉及超过230万个人.
- 综合分析显示,亚洲人的OASIS发病率明显高于白人 (OR,1.64;95%CI,1.48-1.80).
- 南亚亚裔子组的发病率最高,基于人口的研究显示发病率高于基于医院的研究.
结论:
- 产科关节损伤在亚洲分娩个体中比在多个高收入,非亚洲国家的白人个体更为普遍.
- 进一步的定性和定量研究对于确定导致这种观察到的差异的潜在因果机制至关重要.
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