跨喜马拉雅部落人口中的乙型肝炎:高患病率,高儿科负担,病毒学模式,以及对公共卫生干预措施的影响
Brij Sharma1, Vishal Bodh1, Neetu Sharma2
1Department of Gastroenterology, Indira Gandhi Medical College, Shimla, India.
Journal of clinical and experimental hepatology
|January 29, 2024
概括
乙型肝炎在印度部落人口中非常普遍,特别是在5岁以下的儿童中. 这项研究调查了这个脆弱群体的风险因素和病毒概况.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,乙型肝炎病毒 (HBV) 感染对健康构成重大负担.
- 印度的部落人口与非部落社区相比,B型肝炎的患病率不成比例地高.
研究的目的:
- 调查部落人口中与乙型肝炎感染相关的风险因素.
- 描述这一群体中乙型肝炎患者的病毒学和生化特征.
主要方法:
- 从2015年7月到2017年,在希马查尔邦斯皮蒂进行了一项基于社区的研究.
- 从4201名参与者 (成人和儿童) 的血液样本中分析了乙型肝炎表面抗原 (HBsAg),HBeAg,抗HBe Ab和HBV DNA.
- 进行了肝功能测试,包括氨酸转胺酶 (ALT).
主要成果:
- 在23.08%的人群中观察到乙型肝炎表面抗原 (HBsAg) 阳性,在5岁以下的儿童中患病率为13.51%.
- 在生命的第二个十年 (40.83%) 的HBeAg阳性更高.
- 与HBeAg阴性患者相比,HBeAg阳性患者的HBV DNA和ALT水平显著更高 (HBV DNA的P < 0.001,ALT的P = 0.003).
结论:
- 这项研究证实,在受研究的部落人口中,乙型肝炎的患病率很高.
- 5岁以下的儿童是B型肝炎感染的特别脆弱群体.
- 了解病毒学特征对于在部落社区管理乙型肝炎至关重要.
更多相关视频
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
18.8K
06:32Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
Published on: September 19, 2016
10.6K
相关概念视频
Pulmonary Tuberculosis I
243
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
243
Pulmonary Tuberculosis IV
143
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
143
Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180
Pulmonary Tuberculosis II
239
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
239
Pulmonary Tuberculosis III
332
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
332
Probability Laws
40.8K
Overview
40.8K
