Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Conduction System of the Heart01:20

Conduction System of the Heart

1.0K
The cardiac conduction system produces and transmits electrical impulses that prompt myocardial contraction, ensuring efficient heart function. This intricate system ensures that the heart beats in a coordinated and efficient manner, beginning with the atria and then the ventricles. The conduction system optimizes cardiac output by maintaining this precise sequence, which is crucial for adequate blood circulation.
This system relies on the unique properties of nodal and Purkinje cells:...
1.0K
Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

588
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
588
Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

4.4K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
4.4K
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K
Motor Unit Stimulation01:20

Motor Unit Stimulation

1.6K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
1.6K
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

921
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
921

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Squeezing the atrial voltage map with a peak frequency-tailored approach: When no one knows where the microreentrant circuit is.

Heart rhythm·2026
Same author

Epidemiology, economic burden and mortality of atrial fibrillation in a region with very high life expectancy: a contemporary, population-based analysis in Catalonia.

Open heart·2026
Same author

Utilizing existing test results to improve primary prevention in patients with subclinical coronary atherosclerosis: The USE-IT study.

American journal of preventive cardiology·2026
Same author

Ultra-Early Continuous ECG Monitoring for Silent Atrial Fibrillation Diagnosis in Cryptogenic Stroke: The CRIPTOFAST Randomized Controlled Trial.

European journal of neurology·2026
Same author

A tailored approach to cardioneuroablation for reflex syncope and functional bradycardia: results from the ELEGANCE multicentre study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2025
Same author

A Combination of <i>Lacticaseibacillus paracasei</i> CECT 30660 and <i>Bifidobacterium longum</i> subsp. <i>infantis</i> CECT 7210 Cell-Free Supernatants Reduces LPS-Induced Preterm Birth and Systemic Inflammation in Pregnant Mice.

Nutrients·2025

相关实验视频

Updated: Jul 4, 2025

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

14.7K

导电系统刺激以避免左心室功能障碍

Carlos E González-Matos1,2,3,4, Oriol Rodríguez-Queralto1,3, Fátima Záraket1,3

  • 1Electrophysiology Unit, Cardiology Department, Hospital del Mar, Barcelona, Spain (C.E.G.-M., O.R.-Q., F.Z., J.J., B.C., E.V.).

Circulation. Arrhythmia and electrophysiology
|January 29, 2024
PubMed
概括

导电系统节奏 (CSP) 保持左心室功能,并减少心力衰竭住院,与右心室垂节奏 (RVAP) 相比,在需要频繁的心室节奏的患者中. 这项研究强调了CSP作为一种潜在的优越节奏策略.

关键词:
心房动是心房动的一种.心血管阻塞 心血管阻塞心脏再同步治疗心脏再同步治疗人类人类人类人类人类人类.左心室功能,左心室功能

更多相关视频

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.5K
Programmed Electrical Stimulation in Mice
07:29

Programmed Electrical Stimulation in Mice

Published on: May 26, 2010

20.5K

相关实验视频

Last Updated: Jul 4, 2025

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

14.7K
Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.5K
Programmed Electrical Stimulation in Mice
07:29

Programmed Electrical Stimulation in Mice

Published on: May 26, 2010

20.5K

科学领域:

  • 心脏病学 心脏病学
  • 电子生理学 电子生理学
  • 心血管研究研究心血管研究

背景情况:

  • 右心室垂节奏 (RVAP) 与左心室功能障碍有关.
  • 导电系统节奏 (CSP) 已在逆转左心室功能障碍方面表现有前途,但对其在保留射出小部分的患者的预防作用的数据有限.
  • 需要评估CSP在高负荷心室节奏期间预防左心室功能障碍的有效性.

研究的目的:

  • 为了比较CSP与RVAP对保持高心室节奏负担的患者正常心室功能的影响.
  • 与RVAP相比,评估CSP对左心室喷射率 (LVEF) 和左心室尺寸的影响.
  • 评估CSP和RVAP组之间的与心力衰竭相关的住院率.

主要方法:

  • 一项前性,随机,并行,受控的研究,涉及高度心房阻塞和保存或轻微恶化的LVEF (>40%) 的患者.
  • 患者被随机分配,接受传统的RVAP或CSP.
  • 评估结果包括LVEF,左心室终端-透气直径,QRS持续时间和心力衰竭入院6个月后.

主要成果:

  • 七十五名患者被随机分配;70人被纳入治疗意图分析.
  • 与RVAP (160.4±18.1毫秒) 相比,CSP组的刺激QRS持续时间 (124.2±20.2毫秒) 显著较短.
  • 与CSP相比,RVAP组的LVEF显著下降 (-5.8%).与CSP相比,RVAP组的LVEF显著下降. 与CSP相比,RVAP还显示左心室终端透析直径增加和心力衰竭入院率增加 (22.6%与5.1%相比).

结论:

  • 导电系统刺激有效地防止了LVEF恶化,并减少了与心力衰竭相关的住院治疗患者正常或轻度受损的LVEF需要显著的心室节奏.
  • 与RVAP相比,CSP在维持心室功能和减少心脏不良事件方面表现出优异的特征.
  • 这些短期发现需要通过更大规模的长期研究来证实.