评估左心室硬度与心声回声学
Nanjun Zhang1,2, Liting Tang1,2, Linling Zhang1,2
1Department of Pediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Echocardiography (Mount Kisco, N.Y.)
|January 29, 2024
概括
在心力衰竭中评估左心室 (LV) 刚性与保存的喷射分数 (HFpEF) 是至关重要的. 虽然心声回声学提供了非侵入性方法,但目前对LV腔和心肌硬度的指数缺乏可靠性,无法准确评估个体患者.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 医疗成像医学成像
背景情况:
- 保存喷射分数 (HFpEF) 的心力衰竭影响了所有心力衰竭患者的一半.
- 左心室 (LV) 硬度增加是HFpEF的关键病理生理因素.
- 对LV度的侵入性测量是有限的;非侵入性心声回声学方法正在开发中.
研究的目的:
- 在HFpEF中审查LV度的病理生理机制.
- 总结心声回声学衍生的指数,用于评估LV腔和心肌硬度.
- 讨论与侵入性措施的相关性,这些非侵入性指数的应用和局限性.
主要方法:
- 关于对LV度进行心声回声评估的现有文献的综述.
- 对LV室刚度的指数进行分析 (例如,E/e'/LVEDV,E/SRe/LVEDV,DPVQ,TVI).
- 对LV心肌硬度指数的分析 (例如,DWS, iVP, SWI).
主要成果:
- 对LV腔硬度的心声指数 (E/e'/LVEDV,E/SRe/LVEDV,DPVQ) 显示,由于依赖LV填充压力替代品,与侵入性措施存在中度的相关性.
- 时间-速度积分 (TVI) 测量显示出潜力,但需要进一步验证.
- 对LV心肌硬度 (DWS, iVP, SWI) 的心声学指数有局限性;DWS可能反映整体心脏功能,而不是纯硬度.
结论:
- 目前,没有单一的心声回声学衍生指数可靠地评估LV度.
- 目前用于LV腔和心肌硬的非侵入性方法在准确性和可靠性方面存在局限性.
- 使用多个心声回声学参数进行综合评估,可以改善检测LV硬度变化的情况.
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