哨兵节点和隐形损伤定位 (SNOLL) 技术在非可触摸的乳腺损伤中使用单个放射性药物
Berna Okudan1, Bedri Seven2, Pelin Arıcan1
1Department of Nuclear Medicine, Ankara City Hospital, University of Health Sciences, Ankara, Turkey.
Current medical imaging
|January 29, 2024
概括
哨兵节点和隐性损伤定位 (SNOLL) 技术成功地定位了非可触摸的乳腺损伤. 然而,它在识别哨兵淋巴结 (SLN) 的效率需要进一步改进,以获得最佳的患者结果.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 手术病理学手术病理学
背景情况:
- 准确的非触摸性乳腺病变的手术内定位对于完全的手术切除至关重要.
- 哨兵淋巴结 (SLN) 状态是乳腺癌管理中的关键预后指标.
研究的目的:
- 评估哨兵节点和隐性病变定位 (SNOLL) 技术的有效性,用于同时定位非触摸性乳腺病变和SLN.
- 在SNOLL程序中,为了评估单个辐射追踪器,技术-99m标记的人类血清白蛋白 (99mTc-NC) 的纳米聚合物颗粒的实用性.
主要方法:
- 该研究包括39名患有非触摸性乳腺病变的患者,没有临床下病.
- 99mTc-NC的超声导入内注射是在手术当天进行的.
- 病变和SLN的定位使用平面和SPECT/CT淋巴细胞切割仪进行,用马探针指导手术接入并确认完全切除.
主要成果:
- 在所有39名患者中,乳腺病变的成功局部化和移除得到了成功.
- 乳腺癌诊断在11名患者 (28%),良性病变在28名患者 (72%).
- 在79.5%的患者 (31/39) 中发现了哨兵淋巴结,仅在两个病例中发现了转移性参与.
结论:
- 使用内99mTc-NC作为唯一的放射追踪器的SNOLL技术,在局部化非触摸性乳腺病变方面表现出高的成功率.
- 使用这种方法对哨戒淋巴结的鉴定率并不完全令人满意,需要进一步调查.
关键词:
淋巴细胞切割图 (Lymphoscintigraphy) 是一种淋巴细胞切割图.这是SNOLL.没有触摸的乳腺损伤.无线指导手术是指导无线电的手术.无线电追踪器是什么意思护卫淋巴结的护卫淋巴结.更多相关视频
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