在美国,纵向位置和癌症风险的复习
Jin Niu1, Charlotte Brown2, Michael Law3
1Department of Economics, Brown University, Providence, Rhode Island.
Cancer research communications
|January 29, 2024
概括
日光节约时间 (DST) 并没有显著影响整体癌症发病率. 这项研究发现没有实质性证据将夏令时或标准时间与癌症风险联系起来,这挑战了以前的研究,并为正在进行的辩论提供了信息.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 时间生物学 时间生物学
背景情况:
- 关于夏令时间 (DST) 的辩论由于阳光照射变化而影响健康.
- 之前的研究通过比较时区内和跨时区的位置来模拟DST效应.
- 癌症发病率及其与时区内的纵向位置的关系需要进一步研究.
研究的目的:
- 分析癌症发病率与相邻的美国的时区位置相关的情况.
- 调查与夏令时和标准时间相关的人类健康的潜在差异.
- 挑战并提供关于DST和癌症风险的先前研究的新见解.
主要方法:
- 从国家癌症概况中分析了19种癌症类型的癌症发病率数据 (2016-2020年).
- 利用日志线性回归来复制之前的研究.
- 采用空间回归模型和回归不连续性设计,使用自然线条来分析边界不连续性和时区效应.
主要成果:
- 总体癌症发病率在时区或边境附近没有显示出统计学上显著的差异.
- 乳腺癌,前列腺癌,肝癌和胆管癌与纵向位置有一些显著的关系.
- 乳腺和肝脏/胆道癌症的发病率下降,而前列腺癌的发病率在时区内从西到东增加.
结论:
- 这项研究的结果表明,时区位置,以及延伸到中午时间,并没有显著影响整体癌症发病率.
- 针对特定癌症的孤立例外需要进一步调查,提供更多数据.
- 这些结果挑战了先前的研究,并建议重新考虑DST对健康的影响.
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