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Updated: Jul 4, 2025

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host
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在生物共聚焦显微镜鉴定Candida parapsilosis角膜炎的特征

R Scotto1, P Forte, A Macrì

  • 1Clinica Oculistica (R.S., P.F., C.B., C.E.T.), Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DINOGMI), Università degli Studi di Genova, Genova, Italy; and IRCCS Ospedale Policlinico San Martino (P.F., A.M., C.B., C.E.T.), Genova, Italy.

Eye & contact lens
|January 29, 2024
PubMed
概括

这份病例报告强调了Candida parapsilosis作为真菌性角膜炎的原因. 角膜共聚焦显微镜在使用治疗性隐形眼镜和类固醇眼滴的患者中发现了特征性发现,有助于诊断和治疗.

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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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