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Updated: Jul 31, 2026

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging
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针对内质网膜准基纳佐林基脂性探头,用于特定的光诱导性铁亡及其诱导性脂质动态调节

Zhiming Xing1,2, Jiangyu Yan2, Yongxiang Miao1

  • 1Key Laboratory for Green Chemistry of Jiangxi Province, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China.

Journal of medicinal chemistry
|January 29, 2024
PubMed
概括

研究人员开发了新的光激活探头,BODIQPy-TPA和QPy-TPA,以直接诱导和研究被编程细胞死亡中的脂质过氧化,特别是铁亡. 这些探针为ferroptosis期间的脂质调节机制提供了新的见解.

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相关概念视频

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...