实验性2型糖尿病和脂毒性相关的神经炎症涉及线粒体DNA介导的cGAS/STING轴:1型干扰素反应对认知障碍的影响

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Kumari Preeti1, Anika Sood1, Valencia Fernandes1

  • 1Molecular & Cellular Neuroscience Lab, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana, 500037, India.

Molecular neurobiology
|January 29, 2024
PubMed
概括

1型干扰素反应与2型糖尿病 (T2DM) 脑部变化和认知障碍有关. 抑制STING信号可能通过减少神经炎症来保护T2DM相关的神经问题.

关键词:
皮层 皮层 皮层在海马体内,海马体过高血糖症的发生.超脂血症是因为超脂血症炎症 炎症是一种炎症.微质细胞中的微质细胞线粒体DNA是线粒体的DNA.一种类型-1 干扰素反应.

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