多样性诱导的神经动态的平化和弹性
Axel Hutt1, Daniel Trotter2,3, Aref Pariz3,4
1MLMS, MIMESIS, Université de Strasbourg, CNRS, Inria, ICube, 67000 Strasbourg, France.
Chaos (Woodbury, N.Y.)
|January 29, 2024
概括
神经元异质性通过减少动态波动性和对状态变化的易感性来增强神经网络的弹性. 这种多样性,虽然看似不稳定,但矛盾的是,随着时间的推移,它促进了系统的稳定性.
科学领域:
- 计算神经科学是一种神经科学.
- 系统生物学 系统生物学
- 网络动态 网络动态
背景情况:
- 生物系统表现出无处不在的异质性,这丰富了它们的动态.
- 将这种多样性与系统的稳定性和持久性 (弹性) 结合起来是一个关键的挑战.
- 了解神经回路中的弹性机制对于神经科学至关重要.
研究的目的:
- 研究神经回路中兴奋性异质性和弹性之间的关系.
- 阐明异质性影响网络稳定性和稳健性的机制.
主要方法:
- 利用稀疏神经网络的非线性网络模型.
- 在分析和数值上分析了梯度和非梯度系统.
- 通过测量静态状态的数量及其对控制参数的灵敏度来量化弹性.
主要成果:
- 神经元的异质性减少了静止状态的数量,这种现象被称为平化.
- 异质性降低了网络对分叉的易感性,提高了稳定性.
- 异质性作为一个恒温机制,提高适应网络大小和连接概率变化的弹性.
结论:
- 神经元异质性是维持神经网络弹性的一个关键因素.
- 由于异质性而观察到的轻微化效应矛盾地增强了系统的稳定性.
- 异质性提供了恒温控制,减轻动态波动,促进长期持久性.
相关概念视频
Neuroplasticity
361
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
361
Neuronal Communication
947
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
947
Long-term Potentiation
2.8K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
Hebbian LTP
LTP can occur when...
2.8K
Neural Regulation
39.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.4K


