较低的阿片类药物处方量不会在ACL重建后对疼痛控制或患者满意度产生负面影响:一个随机的,前性试验
William L Johns1, Adeeb Jacob Hanna, Henson Destine
1Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, Pennsylvania.
The Journal of bone and joint surgery. American volume
|January 29, 2024
概括
在前十字带重建 (ACLR) 后处方15片阿片类药片提供了与较高剂量相同的疼痛缓解和满意度. 这种方法可以减少未使用的阿片类药物剂量和潜在的转移风险.
科学领域:
- 整形外科手术 整形外科手术
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 前十字带重建 (ACLR) 后的术后疼痛管理通常涉及阿片类药物处方.
- 确定最佳的阿片类药物数量至关重要,以平衡疼痛控制,尽量减少未使用的药物和转移风险.
研究的目的:
- 评估不同量处方阿片类药片对ACLR后患者结局的影响.
- 评估不同处方水平的阿片类药物使用,术后疼痛,功能和患者满意度.
主要方法:
- 一项前性随机试验,涉及接受初级ACLR治疗的患者.
- 患者被随机分配到三个组,接受15,25或35片5毫克的氧化.
- 使用视觉模拟尺度 (VAS) 疼痛评分,药物记录,满意度调查和国际膝关节文档委员会 (IKDC) 问卷来衡量结果.
主要成果:
- 在VAS疼痛得分,IKDC得分或两组之间消耗的吗啡毫克相当量 (MMEs) 中没有发现显著差异.
- 患者对疼痛控制的满意度也显示在处方组之间没有显著差异.
- 在手术后的前三天内,发生了高比例的阿片类药物消费,15片片组中的大多数患者感到足够或过度供应.
结论:
- 处方15片阿片类药片与处方25或35片药片在ACLR后的疼痛控制,满意度和短期功能方面同样有效.
- 降低阿片类药物处方量可以保持足够的疼痛管理,同时减少未使用的阿片类药物剂量的数量,从而减轻转移风险.
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