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Updated: Jun 9, 2026

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聚合的玛原cadherin PcdhγC4异型调节皮质内部神经元编程细胞死亡在小鼠皮质

Walter R Mancia Leon1, David M Steffen1,2, Fiona R Dale-Huang1

  • 1Department of Neurological Surgery and The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143.

Proceedings of the National Academy of Sciences of the United States of America
|January 29, 2024
PubMed
概括

一个特定的protocadherin基因,PcdhγC4,对于调节皮层抑制性内部神经元 (cINs) 在发育过程中的生存至关重要. 它的删除会增加细胞死亡,突出其在平衡神经元数量的作用.

关键词:
它具有GABA活性的作用.抑制性神经元是一种抑制性神经元.介质质突出部的突出部神经元淘汰是神经元的淘汰.移植 移植 移植 移植

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