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Updated: Jul 4, 2025

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
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螺旋式硫-γ-AA,通过识别Aβ螺旋来调节Aβ寡合化和细胞毒性

Heng Liu1, Yunpeng Cui1, Xue Zhao1

  • 1Department of Chemistry, University of South Florida, Tampa, FL 33620.

Proceedings of the National Academy of Sciences of the United States of America
|January 29, 2024
PubMed
概括

通过稳定其α-螺旋结构,新型的硫基--AA螺旋阻碍了粉样β (Aβ) 聚合. 这些化合物抑制Aβ寡合和纤维化,从Aβ诱导的毒性中拯救细胞.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.一个Aβ聚合的Aβ聚合.折叠机 折叠机 折叠机螺旋稳定稳定器 螺旋稳定器硫尼尔-γ-AA类.

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