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岛屿抗原的额外表达增强了T细胞疲劳,以部分预防自身免疫性糖尿病

Claudia Selck1,2, Gaurang Jhala1, David J De George1,2

  • 1Immunology and Diabetes Unit, St. Vincent's Institute, Fitzroy, VIC 3065, Australia.

Proceedings of the National Academy of Sciences of the United States of America
|January 29, 2024
PubMed
概括

通过抗原暴露诱导T细胞耗尽可以预防自身免疫性糖尿病. 这项研究表明,由前体细胞维持的胰腺小岛中的T细胞枯竭可以被利用来保护糖尿病的进展.

关键词:
T细胞耗尽的情况.这是自身免疫力.这是一个宽容的宽容度.第1类糖尿病 1型糖尿病

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