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在为运动障碍进行分阶段深度大脑刺激期间的大脑转移.

Keanu Chee1, Lisa Hirt1, Madelyn Mendlen1

  • 1Department of Neurosurgery, University of Colorado Anschutz Medical Campus School of Medicine, Aurora, Colorado, USA.

Stereotactic and functional neurosurgery
|January 29, 2024
PubMed
概括

在深度脑刺激手术期间,肺头引起的内空气积累并没有显著影响大脑转移. 无论存在空气,平均脑部移位仍然很小 (<1.0毫米),这表明它可能没有临床意义.

关键词:
大脑的转移大脑的转移深度大脑刺激是什么?内空气 内空气这是一种肺脑病 (pneumocephalus).

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科学领域:

  • 神经外科 神经外科
  • 神经学 神经学
  • 医疗成像医学成像

背景情况:

  • 深度大脑刺激 (DBS) 对像帕金森病这样的运动障碍至关重要.
  • 准确的位置对于DBS的有效性至关重要.
  • 由肺脑引起的大脑转移可以降低DBS的准确性.

研究的目的:

  • 为了研究在分阶段的DBS手术中内空气 (肺脑) 和大脑转移之间的联系.
  • 为了确定肺脑病是否会影响DBS程序中的立体学准确性.

主要方法:

  • 对46名患者进行了回顾性分析,这些患者因运动障碍而经历了分阶段DBS.
  • CT成像分析了内空气体积和电极移位.
  • 皮尔森相关性和t测试用于评估空气和转移之间的关系.

主要成果:

  • 在两种电极植入后,肺脑是常见的.
  • 首次植入后的内空气与脑的ipsilateral转移 (y轴和欧几里德距离) 相相关.
  • 在第二次植入后没有发现显著的相关性,并且在有或没有肺脑病患者之间的转移没有显著差异.

结论:

  • 内空气积累,即使高达22.0厘米3,也没有导致临床上显著的脑部转移.
  • 平均脑部移位始终为<1.0毫米,无论肺脑是否存在.
  • 肺脑可能不是DBS手术中大脑转移的重要因素.