与铁相关的炎症标志物在患有结肠的马匹中
P A Canola1, R F de Salles2, E R Daneze2
1Department of Veterinary Medicine and Surgery, São Paulo State University (Unesp), School of Agricultural and Veterinarian Sciences, Via de Acesso Prof. Paulo Donato Castellane, Jaboticabal, São Paulo 14884-900, Brazil.
Journal of equine veterinary science
|January 29, 2024
概括
炎症标志物如哈普托格洛宾,转移素和铁可以帮助诊断马的结肠. 较高的纤维素水平表明,有杀障碍的马匹死亡风险更高.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 马的健康 马的健康
- 生物化学 生物化学
背景情况:
- 窒息性结肠是马的严重疾病,需要及时诊断和治疗.
- 了解炎症标志物可以帮助评估疾病严重程度和预后.
- 铁代谢和急性阶段蛋白 (APP) 在马的炎症反应中起作用.
研究的目的:
- 为了比较和关联健康马的费里丁,转激素,铁和APP的水平,与那些手术治疗喉的马匹相比.
- 为了确定可靠的炎症标志物用于马类结肠.
- 探索这些标志物的预后价值与结果和受影响的肠道部分相关.
主要方法:
- 采集了22匹马的血液样本 (10名健康对照,12名手术治疗结肠).
- 测量包括费里丁,转激素,铁,总蛋白质,纤维素原,专蛋白,哈普托格洛宾和宫质.
- 马被分为控制 (CG) 和阻碍 (OG) 组,OG进一步根据肠道段和结果进行细分.
主要成果:
- 阻塞组 (OG) 的马与对照组 (CG) 相比,表现出较高的哈普托格洛宾和转激素,以及较低的铁含量.
- 患有大肠阻塞的马的转林水平低于患有小肠阻塞的马.
- 费里丁水平与原始植物中的总蛋白质和白蛋白相关. 较高的纤维素素水平与不存活有关.
结论:
- 黑球蛋白,转激素和铁是马科利克有价值的炎症标志物.
- 费里丁可以作为马的急性阶段蛋白质.
- 患有窒息障碍的马的纤维素水平升高与较高的死亡风险有关.
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