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Updated: Jul 4, 2025

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揭开表观遗传密码:人类脏DNA甲基化和染色质动力学在脏疾病发展中的作用

Yu Yan1,2,3,4, Hongbo Liu1,2,3,4, Amin Abedini1,2,3,4

  • 1Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 19014, USA.

Nature communications
|January 29, 2024
PubMed
概括

表观遗传变化,如DNA甲基化,对于慢性病 (CKD) 的发展至关重要. 这些由遗传学影响的变化影响基因表达,并可以预测疾病的进展,提供新的风险分层策略.

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