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57只埃塞俄比亚土著山羊的全基因组资源序列
Shumuye Belay1,2,3, Gurja Belay4, Helen Nigussie5
1Tigray Agricultural Research Institute, Mekelle, Tigray, Ethiopia. shumuyeb@yahoo.com.
Scientific data
|January 29, 2024
概括
埃塞俄比亚 埃塞俄比亚 埃塞俄比亚
科学领域:
- 基因组学就是基因组学.
- 动物科学动物科学
- 人口遗传学 人口遗传学
背景情况:
- 家庭山羊分布在全球,非洲占世界人口的35%.
- 埃塞俄比亚拥有5250万只山羊,主要是由小农和牧民管理的土著陆地品种.
- 这些山羊在非洲之角有着悠久的历史,由游牧牧民引进.
研究的目的:
- 测序和分析来自12个不同的埃塞俄比亚种群的57只山羊的基因组.
- 为埃塞俄比亚山羊生成一个全面的基因组数据集.
- 为研究山羊种群结构,基因组动态和进化史提供资源.
主要方法:
- 来自12个埃塞俄比亚山羊种群的DNA样本使用Illumina NovaSeq 6000平台进行了测序.
- 测序生成了大约2TB的原始数据,平均读取深度为9.71x.
- 高质量的清洁读数 (99.8%) 被映射到山羊参考基因组,产生约2476万个单核酸多态 (SNP).
主要成果:
- 成功测序和绘制埃塞俄比亚山羊基因组.
- 产生了大约2476万个SNP的大量数据集.
- 与参考基因组相比,绘制成功率高 (99.8%),覆盖率高 (99.6%).
结论:
- 生成的基因组数据为埃塞俄比亚山羊种群提供了宝贵的资源.
- 这些SNP可以在各种尺度上阐明人口结构和基因组动态.
- 这项研究有助于了解家养山羊的进化轨迹.
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