暴露于微塑料和人类生殖结果:系统审查
Kathryn Hunt1, Anna Davies2, Abigail Fraser3
1Department of Obstetrics and Gynaecology, North Bristol NHS Trust, Bristol, UK.
BJOG : an international journal of obstetrics and gynaecology
|January 29, 2024
概括
微塑料存在于人类的生殖组织中,如胎盘和. 需要更多的研究来了解它们对人类生育能力和怀孕结果的影响.
科学领域:
- 环境科学 环境科学
- 生殖毒理学 生殖毒理学
- 人类健康 人类健康 人类健康
背景情况:
- 从塑料污染中产生的微塑料越来越多地被检测到人体组织中,包括胎盘和胎儿.
- 虽然动物研究表明有生殖毒性,但人类缺乏关于微塑料对生育能力和怀孕的影响的数据.
研究的目的:
- 综合现有的关于人类生殖组织中微塑料存在的证据.
- 调查微塑料暴露,环境因素和人类生殖结果之间的关联.
主要方法:
- 在多个数据库 (MEDLINE,Embase等) 中进行全面的文献搜索. 在2023年2月之前.
- 包括对人类参与者的研究,评估生殖组织中的微塑料,环境暴露以及生育/怀孕结果.
- 数据提取和叙事合成由于七项纳入研究中的异质性.
主要成果:
- 在七项研究中,来自96名参与者的胎盘和样本中发现了16种聚合物类型的微塑料.
- 生活方式因素与胎盘微塑有关;美微塑与减少肠道微生物群多样性有关.
- 较高的胎盘微塑水平与较低的出生体重和Apgar分数相关.
结论:
- 有限的观察性研究表明,微塑料与生殖健康指标之间存在潜在的关联.
- 高质量的观察性研究对于确定微塑料对人类生殖健康的影响至关重要.
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