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Updated: Jul 4, 2025

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations
11:52

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations

Published on: August 4, 2016

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全长的异形连接测序来解决癌症转录组复杂性的问题

Saranga Wijeratne1, Maria E Hernandez Gonzalez1, Kelli Roach1

  • 1The Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, 575 Children's Crossroad, Columbus, OH, 43215, USA.

BMC genomics
|January 29, 2024
PubMed
概括

我们开发了PacBio全长异形并列体测序 (PB_FLIC-Seq),以增加长读测序输出,改善新型癌症异形的检测. 这种方法增强了儿科质瘤中的异型发现,揭示了显著的细胞外基因表达变化.

关键词:
连锁化是一起发生的情况.发现异形体的发现.长时间读取RNA测序.瘤转录基因组的转录基因组

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