透析患者的呼吸道肉症查:横截面和多中心研究协议
Francini Porcher Andrade1,2,3, Sheila Borges4, César Alencar da Silva Filho5,6
1Ciências Pneumológicas Post-Graduation Programme, Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2400 2º andar, Porto Alegre, RS, 90035-003, Rio Grande do Sul, Brazil. fran_porcher@hotmail.com.
BMC nephrology
|January 29, 2024
概括
这项研究选慢性脏病 (CKD) 患者的呼吸道萨尔科佩尼亚进行透析. 呼吸道肌肉衰弱在CKD患者中很常见,影响通风和氧气输送,可能会恶化.
科学领域:
- 老年学是一门学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 肺部病理学 肺部病理学
背景情况:
- 呼吸道皮症涉及与衰老或慢性病 (CKD) 等疾病相关的呼吸道肌肉衰弱.
- 透析中的CKD患者面临由于流体过载和电解质失衡的风险增加,影响通风和肌肉氧化.
- 这种弱点可能会加剧肉症,影响患者的整体健康.
研究的目的:
- 在经过血液透析 (HD) 和腹腔透析 (PD) 的慢性病患者中查呼吸道萨尔科佩尼亚.
主要方法:
- 观察性,横截面,多中心研究 (2023年3月至2025年3月) 涉及81名透析患者 (41名高强度患者,40名病理患者).
- 通过手握强度低和尾骨肌肉质量 (生物电阻分析) 诊断的萨尔科佩尼亚.
- 呼吸系统的sarcopenia通过低的灵感肌肉强度 (manovacuometry) 在sarcopenic患者中确定;严重程度通过身体 (SPPB,TUG) 和肺 (spirometry) 性能来评估.
主要成果:
- 数据收集正在进行中;结果正在等待.
- 这项研究旨在量化这一群体中呼吸道肉症的患病率和严重程度.
结论:
- 现有的文献主要涉及CKD的呼吸功能,有限的重点是sarcopenia.
- 假设轴性骨架肌肉,像尾肌肉一样,在慢性疾病如CKD中可能会减弱.
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