大量营养素和微量营养素补充剂对COVID-19的影响:一个总体审查
SeyedAhmad SeyedAlinaghi1, Ramin Shahidi2, Hengameh Mojdeganlou3
1Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Journal of health, population, and nutrition
|January 30, 2024
概括
微量营养素,特别是维生素D,在减少COVID-19的严重程度和死亡率方面显示出有希望. 虽然一些微量营养素提供了好处,但维生素C在治疗疾病方面没有表现出任何有效性.
科学领域:
- 营养科学 营养科学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 适当的营养对于免疫功能和疾病预防至关重要.
- 大量营养素 (蛋白质,脂质,碳水化合物) 和微量营养素 (维生素) 是必需的饮食成分.
- 营养在COVID-19预防和治疗中的作用需要进行系统的调查.
研究的目的:
- 系统地审查宏观营养素和微量营养素对COVID-19预防和治疗的影响.
- 综合现有系统审查和元分析的证据.
- 评估特定营养素在管理COVID-19结果中的有效性.
主要方法:
- 进行了全面的数据库搜索 (PubMed,Scopus,Embase,科学网).
- 包括以英语出版的系统审查和元分析.
- 使用Cochrane的偏差风险工具进行了质量评估,并对提取的数据进行了定性合成.
主要成果:
- 二十八个评论被纳入了合成中.
- 微量营养素通常在控制COVID-19发病率和死亡率方面表现出有效性,尽管并非普遍用于严重程度.
- 二醇已成为一种高效的药物,可以降低重症监护室的入院率和死亡率.
结论:
- 营养不良与SARS-CoV-2感染和严重疾病的风险增加有关.
- 维生素D的使用有效地降低了COVID-19的发病率和死亡率;缺乏增加了严重程度的风险.
- 虽然维生素A,B和显示出好处,但维生素C在COVID-19管理中没有被证明的有效性.
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