四十年来,年龄和种族特异性ESKD发病率的变化
Chyng-Wen Fwu1, Paul W Eggers2, Jenna M Norton2
1Social & Scientific Systems, Inc., a DLH Holdings Corp (DLH) Company, Silver Spring, Maryland.
Journal of the American Society of Nephrology : JASN
|January 30, 2024
概括
从1980年到2019年,黑人和白人美国人的末期病 (ESKD) 发病率增加,显著的种族差异仍然存在. 虽然青少年率有所改善,但其他群体的下降速度较慢,这凸显了解决ESKD的持续挑战.
科学领域:
- 科和公共卫生
- 慢性病的流行病学 慢性病的流行病学
- 在医疗保健结果中的种族差异.
背景情况:
- 末期病 (ESKD) 的发病率在过去40年里发生了显著的变化.
- 以前的研究还没有充分探讨ESKD发病率趋势的年龄和种族差异.
- 了解这些趋势对于公共卫生干预和医疗保健政策至关重要.
研究的目的:
- 分析美国不同年龄和种族群体中ESKD发病率的长期趋势.
- 为了识别随着时间的推移ESKD发病率的年度百分比变化 (APC) 的显著变化.
- 为了突出黑人和白人美国人之间ESKD发病率的持续差异.
主要方法:
- 使用美国脏数据系统 (USRDS) 从1980年到2019年的数据.
- 分析了黑人和白人青少年 (13-17岁),成年人 (18-64岁) 和老年人 (≥65岁) 的ESKD发病率趋势.
- 雇佣的关联点回归分析以确定APC和ESKD发病率的显著斜率变化.
主要成果:
- 1980年以后,在所有分析的群体中,ESKD发病率在不同趋势下增加.
- 到1993年,大多数病例的发病率增长放缓,到2006年,除了白人成年人外,APC的发病率下降.
- 到2019年,青少年ESKD发病率接近1980年的水平,但其他群体的改善程度较低;黑人患者在所有年龄组中总是比白人患者的发病率更高.
结论:
- 在不同年龄,性别和种族群体中存在不同的ESKD发病率模式.
- 研究结果表明,透析接受,获得医疗保健,糖尿病和CKD治疗指导方针的潜在影响.
- 需要具体的人口策略来制ESKD的增长,并解决美国的种族差异.
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