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揭示了上腺和甲状腺中主要的外节扩散大B细胞淋巴瘤的发现
Judy Li1, Raisa Balbuena-Merle2, Morgan Hrones3
1Section of Endocrine Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.
The American journal of case reports
|January 30, 2024
概括
主要异位扩散大B细胞淋巴瘤 (DLBCL) 可以模仿上腺和甲状腺的固体器官瘤. 通过活检进行早期诊断对于有效治疗这种侵袭性癌症至关重要.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 血液学 血液学 血液学
背景情况:
- 主要的外节扩散大B细胞淋巴瘤 (DLBCL) 是一种侵略性的恶性瘤.
- DLBCL可以呈现为固体器官瘤,使诊断复杂化.
- 及时诊断对于改善患者预后至关重要.
研究的目的:
- 突出了初级外节腺DLBCL的诊断挑战.
- 为了呈现DLBCL伪装成上腺和甲状腺瘤的病例.
- 强调在差异诊断中考虑DLBCL的重要性.
主要方法:
- 两名患者的病例报告被诊断出患有初级的 extranodal DLBCL.
- 手术切除和组织病理学检查.
- 对上腺和甲状腺质量的诊断方法的审查.
主要成果:
- 案例1:一名69岁的女性患有上腺质量,最初怀疑是上腺皮癌,在手术后被诊断出患有主上腺DLBCL.
- 案例2:一名59岁的女性患有哈西莫托甲状腺炎和喉,在甲状腺切除术后被诊断出患有主要甲状腺DLBCL.
- 这两种病例都表明DLBCL呈现为固体器官瘤.
结论:
- 在对上腺和甲状腺瘤的差异诊断中,应考虑初级的外节DLBCL.
- 活检对确诊的好处必须与手术风险进行权衡.
- 在可行的情况下,应采用评估DLBCL的活检技术,以便及时启动治疗.
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