吃辛食物可以降低缺血性中风的风险:一项前性研究
Jiale Li1, Changping Xie2, Jian Lan2
1School of Public Health of Guangxi Medical University, 22 Shuangyong Road, Nanning, Guangxi, 530021, People's Republic of China.
The British journal of nutrition
|January 30, 2024
概括
经常吃辛食物与中风风险降低有关,特别是缺血性中风. 在每周3-5天食用辛食物的人群中,观察到最大的益处,显示出U形的保护作用.
科学领域:
- 营养流行病学 营养流行病学
- 心血管健康 心血管健康
- 公共卫生 公共卫生
背景情况:
- 以前的研究表明,食用辛食物可能会降低心血管疾病死亡率和中风风险.
- 然而,辛食物摄入频率,中风亚型和剂量反应效应之间的具体关系仍未得到充分研究.
研究的目的:
- 调查辛食物消费频率与发生中风的风险之间的关联,包括缺血性中风 (IS) 和出血性中风 (HS).
- 检查大量前性队列中辛食物摄入量和中风风险之间的剂量反应关系.
主要方法:
- 一项前性队列研究,涉及50174名30-79岁的参与者.
- 辛食品的消费量通过基线问卷进行评估.
- 考克斯的比例危险模型和受限立方线分析被用于评估中位数为10.7年的随访期间的关联和剂量反应关系.
主要成果:
- 总共记录了3967次冲击 (3494次IS,516次HS).
- 与罕见摄入量相比,每月,每周1-2天,每周3-5天的辛食物摄入量与整体中风风险降低有关 (HRs:0.914,0.869,0.826).
- 对于缺血性中风也观察到类似的保护性关联,具有U形的剂量反应关系. 摄入3-5天/周的辛食物显示风险最低.
结论:
- 辛食物的消费与缺血性中风的风险有负面联系.
- 存在一个U形的剂量反应关系,适度的摄入 (每周3-5天) 提供了最重要的保护.
- 进一步的研究可能会阐明这种保护作用背后的具体机制.
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