辅助生殖技术与子女神经发育障碍之间的关联:当前证据概述
Zhitao Zeng1, Zhuoyi Wang2, Pengfei Yu1
1Department of Neurology, Affiliated Hospital of Nantong University, Medical School of Nantong University, 226001 Nantong, Jiangsu, China.
Journal of integrative neuroscience
|January 30, 2024
概括
辅助生殖技术 (ART) 可能会影响儿童的神经发育. 这篇综述考察了ART ART.
科学领域:
- 生殖医学 生殖医学
- 发育神经科学的发展神经科学.
- 遗传学 是一个遗传学.
背景情况:
- 辅助生殖技术 (ART) 的使用越来越多,导致越来越多的ART受孕儿童.
- ART程序涉及将性细胞和胚胎暴露在非生理条件下,可能会影响发育.
- 人们对ART孕育后代的长期健康和神经发育结果存在担忧.
研究的目的:
- 审查当前关于ART对神经发育影响的研究.
- 探索ART,表观遗传变化和神经发育障碍 (NDD) 之间的联系.
- 总结有关自闭症,智力障碍,多动症和脑等NDD的证据. 在ART受孕的个体中.
主要方法:
- 对现有的科学文献进行系统审查.
- 对研究ART对胚胎发育和后代健康的影响的研究分析.
- 专注于研究表观遗传修饰和神经发育结果的研究.
主要成果:
- 讨论了ART对神经发育的潜在影响.
- 通过表观遗传修饰,ART程序可能会影响胚胎发育.
- 有证据表明,ART与某些NDD的风险增加之间可能存在关联.
结论:
- 需要进一步的研究才能充分理解ART对神经发育的影响.
- 未来的研究需要大样本规模和对混因素的控制.
- 跨学科的方法对于监测ART产生的儿童的神经发育轨迹至关重要.
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