局部大麻和延迟发作的肌肉疼痛的进展率
Anastasia Alpy1, George Yusuff1, Troy Simpson1
1Department of Exercise Science, Adelphi University, Garden City NY, USA.
International journal of exercise science
|January 30, 2024
概括
局部使用的大麻 (CBD) 膏并没有减少炎症或疼痛,也没有改善运动引起的肌肉损伤后的表现. 这项研究发现,CBD和安慰剂在延迟发作的肌肉疼痛 (DOMS) 恢复方面没有显著差异.
科学领域:
- 运动医学 运动医学
- 运动生理学 运动生理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 延迟发作的肌肉疼痛 (DOMS) 是劳累性体力活动的常见后果.
- 目前用于DOMS的治疗方法缺乏强大的疗效,促使对新型治疗剂进行研究.
- 在临床前研究中,大麻素 (CBD) 已显示出抗炎和止痛特性.
研究的目的:
- 评估局部大麻 (CBD) 膏在缓解DOMS症状方面的疗效.
- 评估CBD对局部炎症,肌肉力量恢复和感知疼痛的影响.
- 为了比较局部CBD与安慰剂在双盲随机对照试验中的作用.
主要方法:
- 一个双盲,随机对照试验,涉及21名大学年龄的参与者.
- 在双肩臂肌肌中诱导了DOMS.
- 在运动后的多个时间点应用局部CBD或安慰剂膏.
- 测量包括上臂周长,最大自愿同度收缩 (MVICs) 和视觉模拟尺度 (VAS) 疼痛.
主要成果:
- 在CBD和安慰剂组之间,在上臂周长上没有观察到统计学上显著的差异.
- 两组的MVIC都显示出减少,CBD和安慰剂之间没有显著差异.
- 在CBD和安慰剂组中,感知到的疼痛随着时间的推移而增加,没有显著差异.
结论:
- 局部使用的CBD膏在减少炎症,改善肌肉力量或缓解DOMS相关的疼痛方面没有表现出有效性.
- 这些发现表明,局部CBD与安慰剂相比,不会减弱DOMS的生理或感知效应.
- 可能需要进一步的研究来探索CBD用于DOMS管理的不同配方或施用途径.
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