贫血及其相关物质与中国慢性精神分裂症患者的认知功能之间的关系:一项大型横截面研究
Yang Jiang1, Yi Cai2, Yaoyao Lu1
1Guangxi Brain Disease Prevention & Treatment Research Center, Brain Hospital of Guangxi Zhuang Autonomous Region, Liuzhou, Guangxi, China.
Schizophrenia research. Cognition
|January 30, 2024
概括
贫血在精神分裂症患者中很常见,影响超过26%. 然而,这项研究发现贫血和精神分裂症患者的认知衰退之间没有联系. 贫血与年龄较大,女性性别和体重较低有关.
科学领域:
- 精神病学是一个精神病学.
- 血液学 血液学 血液学
- 神经学 神经学
背景情况:
- 精神分裂症 (SCZ) 和贫血可以独立导致认知能力下降.
- 贫血对SCZ患者认知功能的影响尚不清楚.
研究的目的:
- 调查SCZ患者贫血的患病率.
- 检查贫血,SCZ症状严重程度和认知功能之间的关系.
主要方法:
- 从1690名SCZ住院患者收集的人口统计和临床数据.
- 使用PANSS,MMSE和RBANS评估精神症状和认知功能.
- 测量血红蛋白 (HGB) 和红细胞 (RBC) 计数通过例行血液测试.
主要成果:
- 在SCZ患者中,贫血患病率为26.36% (383/1453).
- 贫血的SCZ患者年龄较大,体重较轻,阿波利波蛋白B水平较低.
- 在贫血和非贫血的SCZ患者之间没有观察到认知功能的显著差异.
结论:
- 贫血的高患病率存在于汉族中国SCZ患者中.
- 在SCZ的贫血与人口统计学和临床因素如年龄,性别和体重有关.
- 贫血似乎没有加剧SCZ患者的认知衰退.
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