怀孕6个月和2年后的产前相关心血管风险因素:P4研究
Amanda Henry1,2, George Mangos1,3, Lynne M Roberts1,2
1School of Clinical Medicine, UNSW Medicine and Health, University of New South Wales, Sydney, Australia (A.H., G.M., L.M.R., M.A.B., F.P., A.J.O., G.K.D.).
孕前的妇女在产后两年有血压升高 (BP) 和心血管风险标志物. 建议定期进行查,以控制这种增加的风险.
科学领域:
- 产科和妇科 产科和妇科
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 孕前与长期心血管风险和心血管衰老的早期迹象有关.
- 这项研究调查了怀孕前后两年持续的心血管异常.
研究的目的:
- 为了确定血压和其他心血管指标是否在产后两年内仍然异常,在有先兆子史的妇女中.
- 为了确定未来心血管疾病的持续风险标志物.
主要方法:
- 血压测量使用血计,24小时门诊监测和中央血压.
- 人类测量和生物化学测量是在分娩后六个月和两年收集的.
- 在预先怀孕和正常压力怀孕组之间进行了比较,无论是横截面还是纵横.
主要成果:
- 与正常血压对照相比,孕前的妇女在产后两年内血压显著上升,与正常血压对照相比.
- 更高的体重指数和胰岛素耐药性在产后两年的孕前症组中也更常见.
- 在任何一组中,在分娩后六个月至两年之间没有观察到血压的显著变化.
结论:
- 孕前与持续的高血压和产后两年心血管风险因素的增加有关.
- 较高的体重指数和胰岛素耐药性得分有助于提高未来心血管风险.
- 建议所有有先兆子史的妇女进行常规心血管风险查.
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