泌尿干预中的抗生素预防:谁,什么时候,在哪里?
Filippo Marino1,2,3, Francesco Rossi1,2,4, Rita Murri2,5
1Department of Urology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Urologia
|January 30, 2024
概括
抗生素预防 (AP) 对于在泌尿器科手术期间预防感染至关重要. 根据手术类型和患者因素量身定制AP是必不可少的,因为一些干预措施的耐药性模式不断变化和不清楚的证据.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 预防传染病 预防传染病
- 药理学 药理学是指药理学的学科.
背景情况:
- 周围手术预防旨在通过物理,化学或药理手段减少感染风险.
- 抗生素预防 (AP) 涉及在手术前短期使用抗生素以预防传染性并发症.
- 多药耐药细菌和生态系统的变化使泌尿病学中标准化的AP复杂化.
研究的目的:
- 审查文献和关于尿道手术AP的指导方针.
- 确定药理学预防的最佳药剂,时间和适应症.
- 探索AP可能有益或不必要的场景.
主要方法:
- 文献综述 文献综述 文献综述
- 准则分析指南的分析.
- 关于尿道学AP疗效的证据综合.
主要成果:
- 在许多侵袭性手术和高危患者中,AP对许多侵袭性手术和高危患者有益.
- 在泌尿动力学检查,诊断性囊镜检查或石术时,不建议经常使用AP.
- 通过直肠进行前列腺活检是强制性的,而通过膜活检的证据尚不清楚;它是尿路透镜,PCNL,TURBT,TURP和重大手术的标准.
结论:
- 在泌尿学AP中存在显著的证据差距.
- 患者特异性因素 (并发症,免疫能力) 和干预类型对于AP决策至关重要.
- 对AP进行量身定制的,个性化的方法是必要的,超越一个适合所有人的战略.
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