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Updated: Jul 4, 2025

A Method to Study de novo Formation of Chromatin Domains
00:07

A Method to Study de novo Formation of Chromatin Domains

Published on: August 23, 2019

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聚介导的基因组修饰和基因调节.

Shinsuke Ito1, Takashi Umehara1,2, Haruhiko Koseki1,3

  • 1Laboratory of Developmental Genetics, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

Biochemical Society transactions
|January 30, 2024
PubMed
概括

聚合体抑制复合体1和2 (PRC1和PRC2) 通过创建聚合体染色体域来建立基因抑制. 通过PRC1介导的H2AK119ub1增强了PRC2的活动,通过跨尾沟通促进了这一过程.

关键词:
在CpG岛上.H2AK119ub1 在线观看H3K27me3 在线阅读在PRC1中,在 PRC2 中,PRC2 是 PRC2 的第一个类型.转录的压制转录的压制

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