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Updated: Jul 4, 2025

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一个单独的位点决定了Schistosoma mansoni中的质量反应

Frédéric D Chevalier1, Winka Le Clec'h1, Matthew Berriman2

  • 1Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, Texas, USA.

Antimicrobial agents and chemotherapy
|January 30, 2024
PubMed
概括

史基斯托组中普拉西 (PZQ) 药物反应是由单个基因位点控制的,而不是以前认为的两个基因位点. 高质量的基因组数据对于精确的遗传研究至关重要.

关键词:
药物耐药性 耐药性 药物耐药性基因测绘 基因测绘 基因测绘性性性性

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Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
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