评估左心房应变率和左心室静脉应变率作为心脏功能障碍的标志物,在患有 mitra annular 化的患者中使用
Edward W Chen1, Zubair Bashir2, Jessica L Churchill2
1Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
The international journal of cardiovascular imaging
|January 30, 2024
概括
左心房应变和早期的透析应变率并不能准确预测左心室填充压力升高的中心环结的患者. 在常规临床使用之前需要进一步的研究.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 扩张功能评估 扩张功能评估
背景情况:
- 中心环状化 (MAC) 复杂化了标准心声回声学对透静功能的评估.
- 左心房 (LA) 应变和早期透气应变率 (DSr) 是评估透气功能的新兴非侵入性方法.
- 斑点跟踪回声心脏图 (STE) 用于测量LA菌株和DSr.
研究的目的:
- 评估LA菌株和早期DSr在预测MAC患者左心室填充压力升高 (LVFP) 的有用性.
- 为了比较LA菌株和早期DSr的有效性,与额头流入速度E/A比率在预测升高的LVFP.
主要方法:
- 包括接受过胸前心声图 (TTE) 和心脏导管测量LVFP的MAC成年患者.
- 斯皮尔曼的等级相关性和接收器操作特征 (ROC) 曲线被用来评估关联和歧视能力.
- 分析了LA水库应变,平均早期DSr和E/A比率的预测能力.
主要成果:
- 在LA储菌株中,高LVFP的相关性 (rho=0.03) 和区分能力 (AUC=0.54) 较差.
- 平均早期的DSr也表明LVFP升高的相关性较差 (rho=-0.19) 和区分能力 (AUC=0.59).
- 无论是LA菌株还是早期的DSr,单独或与E/A比率相结合,都没有显著改善与单独的E/A比率相比,LVFP升高的预测.
结论:
- 在这项研究中,LA储菌株和早期的DSr被发现是MAC患者腹缩充压的不准确预测器.
- 需要进行额外的研究,以确定LA菌株和早期DSr的临床适用性,以评估MAC患者的填充压力.
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