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Updated: Jul 4, 2025

Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes
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Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes

Published on: September 25, 2013

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在保存界面上的PUF合作伙伴相互作用塑造了Caenorhabditis elegans中的RNA结合格局和细胞命运

Brian H Carrick1, Sarah L Crittenden1, Fan Chen2

  • 1Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

Developmental cell
|January 30, 2024
PubMed
概括

蛋白质-RNA相互作用是生物学中的关键. 一种特定的蛋白质FBF-2使用铁素479与其他蛋白质合作,控制细胞命运和C. elegans的基因调节.

关键词:
这里是C. elegans.在FBF-2中.结合FBF的约束要素在PUF/PUM合作伙伴蛋白质中.在PUF/PUM-RNA结合蛋白中.配合RNA结合的景观eCLIP eCLIP 是一个生殖系干细胞的生殖系干细胞.在gld-1RNARNA中,精子/卵子命运决定决定决定

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