胸腔腹腔食道切除术:当时和现在
John O Barron1, Eugene H Blackstone2, Thomas W Rice1
1Department of Thoracic and Cardiovascular Surgery, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.
The Annals of thoracic surgery
|January 30, 2024
概括
左胸腹食道切除术 (TAE) 可以是一个安全有效的方法,用于食道癌症,当在高体积进行时,显示与其他方法相比的结果. 这项研究评估了TAE.
科学领域:
- 手术瘤学手术瘤学
- 胸部外科手术 胸部外科手术
- 消化道癌研究 消化道癌研究
背景情况:
- 左胸腹食道切除术 (TAE) 是一种用于食道癌的开放性手术方法,其实用性和结果受到争议.
- 这项研究调查了TAE的全球利用率,生存率和当前的机构结果.
研究的目的:
- 为了比较全球TAE与非TAE对食道癌的治疗方法的结果.
- 评估TAE在一个大批量机构的当代使用和结果.
主要方法:
- 使用了全球食道癌协作数据库 (8854名患者,2005年至2014年).
- 员工倾向得分匹配分析,比较全球TAE与非TAE,以及机构大批量TAE与全球非TAE.
- 分析了2017-2021年的机构TAE数据,以获得当前的结果.
主要成果:
- 在全球范围内,TAE患者的淋巴结切除数量更多 (20对17),但与非TAE患者相比,5年生存率较低 (34%对42%).
- 大量的机构TAE显示了与全球非TAE相似的3年生存率 (52%对54%).
- 最近的机构TAE (2017-2021) 患病率低 (5.6%的肺炎) 和高存活率 (98%活在30天).
结论:
- 当TAE作为主要方法在大量环境中进行时,其结果与非TAE具有相似的结果和较低的发病率.
- 对于患有骨干肥胖,先前腹部手术或需要进行广泛切除的局部晚期心脏瘤的患者来说,TAE特别有益.
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