一项关于胆固醇囊与胰腺炎的流行率的观察性研究:地理影响和管理
Shalini G Hegde1, Prassanna Venkatesh1, Elaine A Mathew2
1Department of Paediatric Surgery, St. John's Medical College Hospital, Bangalore, Karnataka, India.
Journal of pediatric gastroenterology and nutrition
|January 31, 2024
概括
这项研究发现,40.2%的印度儿童患有胆固醇囊 (CDC) 也患有胰腺炎,其中很大一部分患有慢性胰腺炎. 这种并发症可能是印度次大陆独有的.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 胆道囊 (Choledochal cyst,CDC) 是一种罕见的胆道通道先天性异常.
- 胰腺炎是众所周知的疾病预防控制中心的并发症,但在这种情况下,慢性胰腺炎的了解很少,特别是在儿科患者中.
- 印度次大陆可能对CDC及其并发症有独特的流行病学模式.
研究的目的:
- 分析印度儿童患胰腺炎的患病率和危险因素.
- 调查对这些患者进行干预的需要.
- 专注于儿童疾病预防控制中心慢性胰腺炎的发生和特征.
主要方法:
- 在11年的时间里,对患有CDC的儿童的医疗记录进行了回顾性审查.
- 使用INSPPIRE指南 (酶升高或放射性成像) 识别胰腺炎.
- 仅患有疾病预防控制中心的儿童与患有疾病预防控制中心和胰腺炎的儿童之间的风险因素比较.
主要成果:
- 40.2%的患有疾病预防控制中心的儿童出现了胰腺炎.
- 患有胰腺炎的儿童的年龄明显高,总 bilirubin,间接 bilirubin,需要更多的干预措施.
- 在患有放射性胰腺炎的患者中,47%的患者表现出慢性胰腺炎的成像特征.
结论:
- 胰腺炎是印度儿童胆固醇囊的常见并发症.
- 慢性胰腺炎,以前没有在儿童疾病预防控制中心报告,似乎在这个队列中普遍存在.
- 这些发现表明,CDC的慢性胰腺炎可能是印度次大陆特有的独特实体.
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