维护比率受损螺旋计患者的死亡风险:评估身体活动的作用
C-C Shu1,2, M K Tsai3,4, J H Lee3
1Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
QJM : monthly journal of the Association of Physicians
|January 31, 2024
概括
身体活动显著降低了保留比率受损螺旋计 (PRISm) 患者的死亡率. 在这个人群中,满足运动建议将所有原因和心血管疾病死亡率的过量降低三分之二.
科学领域:
- 肺部医学 肺部医学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 保留比率受损螺旋计 (PRISm) 与所有原因死亡率的增加有关.
- 之前的研究没有研究过减轻这种风险增加的干预措施.
研究的目的:
- 研究身体活动 (PA) 对PRISM患者死亡率的影响.
- 确定遵守PA指南是否可以降低PRISM患者的死亡风险.
主要方法:
- 这是一项从1994年到2018年对461,183名台湾成年人的前性队列研究.
- 不活跃个体与每周150分钟PA的人之间的死亡风险的比较.
- 考克斯比例危险模型和生命表方法用于分析死亡率和预期寿命.
主要成果:
- 14.3%的队列有PRISm,其中53.1%是身体不活跃的.
- 不活跃的PRISM患者面临28%更高的全因死亡率,45%更高的心血管疾病 (CVD) 死亡率,67%更高的呼吸道疾病死亡率,失去3年的预期寿命.
- 在PRISM患者中,遵守PA建议将所有原因的过度死亡率从28%降低到9%,心血管疾病死亡率从45%降低到15%.
结论:
- PRISm影响了相当一部分人口 (14.3%),并将预期寿命缩短了3年.
- 坚持体育活动 (150分钟/周) 与PRISM患者的多余全因和心血管疾病死亡率减少三分之二有关.
- 在PRISM个体中促进PA是非常有益的,尽管并不是完全消除风险.
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