在COVID-19后,神经化合物肌肉动作潜力,启发性肌肉强度和运动能力下降
Karin Vonbank1,2, Helena Nics3, Ralf Harun Zwick4
1Klinik Pirawarth in Wien, Vienna, Austria.
Frontiers in neurology
|January 31, 2024
概括
由于隔膜肌肉纤维损伤,COVID-19幸存者可能会经历长时间的呼吸问题,影响运动能力和神经功能. 这项研究突出了感染后持续的运动性呼吸障碍的潜在原因.
科学领域:
- 肺部病理学 肺部病理学
- 神经学 神经学
- 运动生理学 运动生理学
背景情况:
- COVID-19可能导致持续的呼吸道症状,包括炼性呼吸不良.
- 呼吸道肌肉衰弱是即使在轻微的COVID-19感染后也报告的一种并发症.
研究的目的:
- 评估神经功能和灵感肌肉容量.
- 为了评估COVID-19后长期呼吸不良的患者的心肺运动能力.
主要方法:
- 这是一项对22名COVID-19后患者的观察研究.
- 进行了神经,呼气肌强度,肺功能,6分钟步行距离和心肺运动测试的电生理学测试.
主要成果:
- 观察到运动能力降低 (预测W峰值%,预测VO2峰值%) 和最大吸气压力 (MIP).
- 六名患者在正常神经传导速度下显示了神经化合物肌肉动作潜力 (CMAP) 的降低,这表明肌肉纤维问题.
- 在CMAP减少的患者中,发现了6分钟步行距离,生活质量和MIP之间的积极相关性.
结论:
- 在COVID-19后,呼吸道肌肉衰弱和运动能力下降与神经病变无关的神经CMAP减弱有关.
- 隔膜肌纤维病理可能导致COVID-19感染后的呼吸系统症状延长.
相关概念视频
Assessment of Airway, Skin Color, and Use of Accessory Muscles
1.0K
A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
Introduction
The initial evaluation of a patient's respiratory system...
1.0K
Hyperpnea and Hyperventilation
1.1K
Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
1.1K
Disorders of the Skeletal Muscle
953
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
953
Mechanism of Breathing III: The Accessory Muscles
2.4K
The Role of Accessory Muscles in the Respiratory System
The respiratory system is a complex network that relies on primary respiratory muscles like the diaphragm, but also involves accessory muscles to enhance lung expansion and airflow during both inhalation and exhalation.
Enhancing Inhalation with Accessory Muscles:
Accessory muscles such as the sternocleidomastoid, scalene, intercostal, and abdominal muscles are crucial when additional respiratory effort is required, such as during deep...
The respiratory system is a complex network that relies on primary respiratory muscles like the diaphragm, but also involves accessory muscles to enhance lung expansion and airflow during both inhalation and exhalation.
Enhancing Inhalation with Accessory Muscles:
Accessory muscles such as the sternocleidomastoid, scalene, intercostal, and abdominal muscles are crucial when additional respiratory effort is required, such as during deep...
2.4K
Skeletal Muscle Relaxants: Adverse Effects
373
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
Unlike...
373
COPD: Pathogenesis and Clinical Features
274
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
274


