在老年人中开发和验证基于名录的风险预测模型来预测老年人死亡率
Jun Duan1, MingXia Wang2, Napoleon Bellua Sam3
1Department of Medical Record Statistics, Peking University Shenzhen Hospital, Shenzhen, China.
SSM - population health
|January 31, 2024
概括
这项研究开发了一种经过验证的中国老年人死亡风险预测模型,使用了综合健康和生活方式数据. 该模型准确地预测了全因死亡率,为公共卫生和临床应用提供了潜力.
科学领域:
- 老年学与公共卫生
- 流行病学和生物统计学
背景情况:
- 预测老龄化人口的全因死亡率对于公共卫生和临床决策至关重要.
- 现有的模型可能无法完全捕捉不同老年人群中影响死亡率的因素的复杂相互作用.
研究的目的:
- 构建和验证中国老年人全因死亡率的综合预测模型.
- 确定与死亡率相关的主要人口,功能和生活方式风险因素.
主要方法:
- 利用中国长度健康寿命调查 (CLHLS) 的数据用于模型导出和验证队列 (HABCS,CHARLS).
- 用拉索回归来选择风险因素,并使用考克斯的比例危险模型来开发方程.
- 使用一致性指数 (C指数) 和交叉验证技术评估模型性能.
主要成果:
- 最终的模型包括年龄,性别,婚姻状况,认知功能,日常生活活动,吸烟史和休活动.
- 在衍生队列中获得0.728的C指数,并通过0.761 (CHARLS) 和0.713 (HABCS) 的C指数进行外部验证.
结论:
- 为中国老年人开发了一种可靠且经过验证的死亡风险预测工具.
- 鉴定到的预测因素为公共卫生战略和临床风险评估提供了宝贵的见解.
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