相关实验视频

Updated: Jul 20, 2026

Using the Race Model Inequality to Quantify Behavioral Multisensory Integration Effects

Using the Race Model Inequality to Quantify Behavioral Multisensory Integration Effects

Published on: May 10, 2019

全球神经科学临床试验中的种族和民族多样性

Loes Rutten-Jacobs¹, Tammy McIver², Adriana Reyes³

¹Product Development Neuroscience, F. Hoffmann-La Roche Ltd, Basel, Switzerland.

Contemporary clinical trials communications

|January 31, 2024

概括

种族和民族少数群体在全球神经科学临床试验中代表性不足,这影响了研究的概括性. 需要新的策略,以确保在未来的研究中纳入多样化的参与者.

科学领域:

神经科学临床试验神经科学临床试验
临床试验多样性临床试验多样性
卫生公平性健康公平性

背景情况:

种族和民族少数群体在神经科学试验中的代表性仍然不足,尽管有多样性的努力.
这种代表性不足可能导致发现的概括性降低,并错过了疗效或安全差异.
不平等的参与机会可能是导致这些差异的一个因素.

研究的目的:

分析和总结全球神经科学临床试验参与者的种族和种族分布.
将试验人口统计数据与国家人口数据进行比较,以确定代表人数不足或代表人数过多.
突出需要改善临床研究的多样性.

主要方法:

全球F.霍夫曼-拉罗什神经科学临床试验数据库的回顾性审查 (2016年2月 - 2021年2月).
种族和种族数据的分层按治疗区域和国家.
试验参与者的人口统计数据与美国,加拿大和英国的国家人口数据的比较.

主要成果:

分析包括来自47个国家的8015名参与者;85.6%是白人,7.1%是亚洲人,1.6%是黑人.
在几乎所有试验中,黑人人群的代表性不足,而白人人群占主导地位.
在美国,西班牙裔/拉丁裔代表 (7.3%) 比普通人口 (16.4%) 低.

结论:

调查结果强调了少数群体在神经科学研究中的持续不足.
在临床研究设计中,需要提高认识和创新方法.
未来的研究必须优先考虑能够更好地反映整体人口多样性的设计.

关键词:

在CNS中,CNS是CNS.临床试验中的临床试验.多样性多样性多样性多样性包容包容包容包容包容种族种族种族种族试验设计试验设计.

更多相关视频

Employing Transcranial Magnetic Stimulation in a Resource Limited Environment to Establish Brain-Behavior Relationships

Employing Transcranial Magnetic Stimulation in a Resource Limited Environment to Establish Brain-Behavior Relationships

Published on: April 20, 2022

Author Spotlight: Increasing TMS Accessibility Through Braiding Techniques for Diverse Hair Types

Author Spotlight: Increasing TMS Accessibility Through Braiding Techniques for Diverse Hair Types

Published on: August 9, 2024

相关概念视频

Clinical Trials

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...

Clinical Trials: Overview

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...