加拿大与抗菌素耐药性感染相关的医院和相关资源成本,2019年
Alan Diener1, Hui Wang1, Miriam Nkangu2
1Policy Research, Economics, and Analytics Unit, Strategic Policy Branch, Health Canada, Ottawa, ON.
来自MRSA和C. difficile的抗菌素耐药性 (AMR) 感染在2019年导致加拿大超过1.25亿美元的医院费用. 这些耐药性感染还导致了大量的间接成本和1,743例过早死亡.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 传染性疾病 传染性疾病
背景情况:
- 抗微生物药物耐药性 (AMR) 由于长时间住院,增加发病率和死亡率以及不断上升的医疗保健成本,造成了重大的社会负担.
- 关键的抗菌素耐药性病原体,如耐甲基金色葡萄球菌 (MRSA) 和困难 Clostridioides (C. difficile),在很大程度上导致了这一负担.
研究的目的:
- 估计2019年加拿大与MRSA和C. difficile感染相关的直接医院费用.
- 量化与这些感染相关的间接资源成本,包括因残疾和过早死亡而失去的生产力.
主要方法:
- 使用放电摘要数据库进行两步分析:估计病例数量和推导每个病例的平均成本.
- 使用回归模型来计算成本,控制人口和混变量.
主要成果:
- 2019年,加拿大记录了16070例C. difficile病例和9889例MRSA感染病例.
- 这些感染导致估计有1,743人过早死亡,主要在老年人群中.
- 医院的直接成本超过了1.25亿美元,间接资源成本从1880万美元到14699万美元不等.
结论:
- 量化AMR感染对经济的影响对于为政策决策提供信息至关重要.
- 这项研究提供了关于特定耐药生物体的总经济负担的重要数据,有助于理解AMR的更广泛影响.
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