适度强度的运动可以通过影响脏微生物组合来保护心脏功能
Jie Xiao1,2,3, Xing Chen1,2,3, Weina Guo4
1Department of Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
iScience
|January 31, 2024
概括
适度运动可以通过改变脏微生物组合和增加Treg细胞来保护心脏功能. 这项研究探讨了小鼠运动强度,脏微生物和心脏健康之间的联系.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 心脏病学 心脏病学
背景情况:
- 身体炼有益于心肺健康,可能通过减少炎症,但机制仍在争论中.
- 脏微生物群因其在免疫调节中的作用而越来越受认可.
- 运动,脏微生物群和心脏功能之间的相互作用需要进一步研究.
研究的目的:
- 研究运动强度,脏微生物组合和心脏功能之间的关系.
- 探索特定细菌,如Lactobacillus johnsonii在调解炼效果中的潜在作用.
主要方法:
- 使用高脂肪饮食和运动小鼠模型.
- 在不同强度的运动中分析了脏微生物组的组成.
- 在小鼠中评估Treg细胞水平和心脏功能.
主要成果:
- 运动强度影响了脏微生物组合,Treg细胞水平和心脏功能.
- 在Lactobacillus johnsonii丰富度和Treg细胞水平之间观察到正相关性.
- 中等强度的运动显示出对心脏功能保护的潜力.
结论:
- 适度强度的运动可以通过调节脏微生物组来保护心脏功能.
- 牛乳杆菌 (Lactobacillus johnsonii) 可能在Treg细胞生产中发挥作用,将运动与免疫和心脏益处联系起来.
相关概念视频
Exercise and Cardiovascular Response
812
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
812
Exercise and Cardiac Output
1.0K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
1.0K
Pathophysiology of Cardiac Performance
663
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
663
Exercise and Muscle Performance
1.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.4K


