在肯尼亚卡吉阿多县使用三种血清学测试对畜牧兽病的血清流行率和空间分布
Mahacla O Odongo1, Lilly C Bebora1, James K Gathumbi1
1Department of Veterinary Pathology, Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Nairobi, Nairobi, Kenya.
Open veterinary journal
|January 31, 2024
概括
牛病在卡吉亚多县的牛群中适度流行,在绵羊和山羊中发病率较低. 间接ELISA对牛来说是最好的,而竞争性ELISA对绵羊和山羊来说是最好的,有助于控制策略.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 动物传播疾病 动物传播疾病
- 流行病学 流行病学
背景情况:
- 兽病是一种严重的动物传播疾病,影响着全球的牲畜和人类健康.
- 肯尼亚面临着流行性百菌病,监测数据有限,特别是在卡吉阿多县.
- 卡吉阿多县动物病菌的真实负担和分布在很大程度上是未知的.
研究的目的:
- 确定目前在卡吉阿多县的畜牧兽病的血清流行率和空间分布.
- 为了比较孟加拉板测试 (RBPT),间接ELISA (i-ELISA) 和竞争ELISA (c-ELISA) 的诊断性能.
主要方法:
- 一项涉及782个未接种疫苗的牛,绵羊和山羊血清样本的横截面研究.
- 样本并行使用RBPT,i-ELISA和c-ELISA对抗布鲁塞拉抗体进行查.
主要成果:
- 动物总体血清流行率为6.91%. 牛的血清流行率为18.35%,绵羊为0.78%,山羊为0.4%.
- 根据测试不同,牛血清流行率有所不同:RBPT (2.2%),i-ELISA (14.4%),c-ELISA (4.7%). 只有通过c-ELISA检测到羊和山羊的阳性.
- 牛群的血清阳性高达67.65%,与羊群 (8%) 和山羊群 (3.6%) 相比.
结论:
- 在卡吉阿多县,牛群中血清病发病率中等,羊群和山羊群中发病率低.
- i-ELISA在检测牛体牛病方面表现优异,而c-ELISA在绵羊和山羊方面表现更好.
- 这项研究为布鲁塞拉感染研究和该地区布鲁塞洛症控制战略的制定提供了必要的基线数据.
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