冠状动脉样硬化和牙周炎在临床表现上有相似之处
Marcelo Barbosa De Accioly Mattos1,2, Camila Bernardo Peixoto1, José Geraldo de Castro Amino3
1School of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Frontiers in oral health
|January 31, 2024
概括
牙周炎 (PE) 与冠状动脉心脏病 (CHD) 有关. 活跃PE与更多和更大的冠状动脉动脉瘤相关,表明共享的进展途径和干预的潜力.
科学领域:
- 心血管医学 心血管医学
- 牙周病学 牙周病学
- 微生物学 微生物学
背景情况:
- 牙周炎 (PE) 和冠状动脉心脏病 (CHD) 分享潜在的病因机制.
- 调查牙周状况与冠状动脉疾病之间的关联对于公共卫生至关重要.
研究的目的:
- 为了比较患有和没有心脏病的患者的牙周状况.
- 为了调查牙周病原体在动脉瘤病变中的存在.
主要方法:
- 一项涉及161名受试者的病例控制研究,根据心血管疾病状态和动脉瘤的存在进行分类.
- 数据收集包括医疗记录,牙周检查,问卷和血管分析.
- 用PCR对特定病原体进行小微生物分析的瘤病变和下斑块.
主要成果:
- 患有心血管疾病的受试者表现出较高的炎症标志物和较低的HDL水平.
- 晚期牙周炎和更多的动脉瘤病变显著相关.
- 患有晚期牙周炎的受试者患心脏病的可能性高出四倍.
结论:
- 冠状动脉心脏病和牙周炎具有相似的进展模式.
- 活跃性牙周炎与动脉瘤病变的数量和大小增加有关.
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