在免疫受损患者的mycobacterium szulgai肺部感染
Sara Neves1, Ema Pos1, Ana Horta1
1Infectious Diseases Department, Centro Hospitalar Universitário de Santo António, Porto, PRT.
Cureus
|January 31, 2024
概括
菌根杆菌 (Mycobacterium szulgai) 是一种罕见的非结核性菌根杆菌感染的原因. 这一案例突显了阿达利穆马布使用与患有潜在疾病的患者中M. szulgai感染之间的潜在联系.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 非结核性真菌菌 (NTM) 是日益公认的病原体.
- 苏尔盖菌 (M. szulgai) 是一种罕见的NTM物种,于1972年确定.
- M. szulgai感染不常见,占所有NTM病例的<0.2%.
研究的目的:
- 报告一个罕见的Mycobacterium szulgai感染病例.
- 为了突出瘤坏死因子-α抑制剂和NTM感染之间的潜在关联.
- 强调在具有相关风险因素的患者中考虑NTM的重要性.
主要方法:
- 一个23岁的女性患者的病例报告.
- 审查患者的病史,包括儿童肺炎和克罗恩病.
- 治疗方案的分析,包括阿达利穆马布 (瘤缩因子α抑制剂).
主要成果:
- 患者出现了暗示真菌细菌感染的症状.
- 病原体被确定为Mycobacterium szulgai. 这种病原体被确定为Mycobacterium szulgai.
- 感染发生在治疗克罗恩病的阿达利穆马布治疗的背景下.
结论:
- 菌素 (Mycobacterium szulgai) 感染很少见,但可能发生在免疫功能低下的人身上.
- 使用瘤坏死因子-α抑制剂可能会增加严重感染的风险,包括NTM.
- 临床医生应在接受免疫抑制疗法且出现相关症状的患者中保持对NTM的高怀疑指数.
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