前接触体育运动参与者的痴呆症危险因素:前性队列研究
G David Batty1, Steven Bell2,3, Urho M Kujala4
1Department of Epidemiology and Public Health, University College London, London, UK.
medRxiv : the preprint server for health sciences
|January 31, 2024
概括
退休的接触体育运动员没有比普通人群更高的痴呆症风险因素. 研究结果表明,其他因素,如头部冲击,可能解释了这些运动员中更高的痴呆率.
科学领域:
- 神经学 神经学
- 运动医学 运动医学
- 流行病学 流行病学
背景情况:
- 在退休接触体育运动参与者中观察到痴呆症发病率升高.
- 假设:运动员中已确定的痴呆风险因素的更高患病率可能解释了这一观察.
研究的目的:
- 调查与一般人口对照组相比,前精英接触体育运动运动员中确定的痴呆风险因素的患病率.
- 确定这些风险因素是否解释了接触体育运动参与者的痴呆症发病率升高.
主要方法:
- 对前精英足球,拳击和摔参与者的队列研究 (1920-1965).
- 从医学检查记录中确定的人口控制组.
- 通过医院登记 (1970-2015年) 和调查问卷 (1985年,1995年) 收集的9个痴呆风险因素的数据.
主要成果:
- 几乎没有证据表明,在前接触体育运动运动员中,痴呆风险因素的流行率较高.
- 前运动员表现出更有利的风险因素水平,特别是吸烟和体育活动.
- 曾经吸烟的几率比率从0.32 (摔) 到0.52 (足球) 不等.
- 休时间体育活动的β系数在1.34 (足球) 到1.80 (拳击) 之间.
结论:
- 检查的风险因素无法解释退休接触体育运动参与者的痴呆率增加.
- 接触体育运动的其他特征,如重复的头部撞击,也与此有关.
- 需要进一步的研究来了解接触体育和痴呆症之间的关系.
相关概念视频
Dementia
115
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
115
Alzheimer's Disease: Overview
487
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
487


