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Updated: Jul 4, 2025

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
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AFF3的变异特异性病理生理机制不同地影响转录组配置文件

Sissy Bassani1, Jacqueline Chrast1, Giovanna Ambrosini2,3

  • 1Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

medRxiv : the preprint server for health sciences
|January 31, 2024
PubMed
概括

AFF3基因功能的微小变化导致KINSSHIP综合征,导致智力障碍和发育问题. 在AFF3中,功能丧失和主导负变异都是有害的,影响基因表达和细胞通路.

关键词:
异构体是什么?异构体是什么?异构体是什么?马的脏 马的脏智力障碍 智力障碍是一种智力障碍.介质性失育症 (Mesomelic Dysplasia) 是一种细胞失育症.转录组 (transcriptome) 是一个转录组.

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