癌症疫苗的现状和未来:一项文献研究
Rui Yu1, Fangmin Zhao1, Zeting Xu1
1The First School of Clinical Medical, Zhejiang Chinese Medical University, Hangzhou, China.
Heliyon
|January 31, 2024
概括
癌症疫苗是瘤免疫治疗的新兴领域,研究正在迅速扩大. 未来的研究可能将重点放在免疫检查点抑制剂和瘤微环境上.
科学领域:
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
- 生物技术是生物技术.
背景情况:
- 癌症疫苗对于瘤免疫疗法至关重要,提供显著的临床益处.
- 精准医学的进步凸显了个性化癌症疫苗向的重要性.
- 缺乏对全球癌症疫苗研究趋势的综合文献统计审查.
研究的目的:
- 进行全球癌症疫苗研究的图书统计分析.
- 识别科学成果,趋势和该领域的新兴热点.
主要方法:
- 关于癌症疫苗的出版物从科学网络核心集合中获取.
- 使用Microsoft Excel,VOS Viewer和CiteSpace V进行了定量和视觉分析.
- 数据包括1991年至2022年以英语出版的文章和评论.
主要成果:
- 在1991年至2022年期间,共发表了7,807篇文章,显示出年增长.
- 美国在出版物,引文和H指数方面处于领先地位,国家卫生研究院是主要机构.
- 关键的研究热点包括瘤微环境,免疫检查点抑制剂,粒子疫苗,瘤抗原和树突细胞.
结论:
- 癌症疫苗在瘤免疫疗法中代表着一个重要的和不断扩大的研究领域.
- 未来的研究很可能集中在免疫检查点抑制剂,瘤微环境和树突细胞上.
- 克服T细胞抑制仍然是癌症疫苗开发中的一个关键挑战.
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